Why can’t I get high? If you’ve ever asked this question, you’re not alone. Many factors can influence your experience with cannabis, from your consumption method to your individual physiology. At WHY.EDU.VN, we delve into the science behind the high and explore the common reasons why you might not be feeling the effects you expect, offering insights and potential solutions. Let’s explore how things such as endocannabinoid deficiency and even hormones can block the effects of cannabis.
1. What Does It Mean to Be High on Cannabis?
The term “high” refers to the altered state of mind induced by consuming or smoking tetrahydrocannabinol, commonly known as THC. For millennia, humans have cultivated and used cannabis to achieve this altered state. While experiences differ depending on the strain, the core experience includes an elevated mood, deep thoughts, heightened appetite, and boosted creativity. Individual reactions can vary, but millions of cannabis enthusiasts worldwide report similar effects.
1.1 How a Cannabis High is Established in the Body
When cannabis is inhaled, THC enters the bloodstream via the lungs. Studies, such as those by Daneman & Prat in 2015, show that THC then circulates through the body and crosses the blood-brain barrier. Once in the brain, THC interacts with the endocannabinoid system (ECS), specifically binding to CB1 receptors. This interaction triggers various effects, including increased dopamine levels, resulting in the classic psychotropic effects of cannabis.
Edibles follow a different path. When THC is ingested, it passes through the digestive system and is absorbed by the liver. The liver converts THC into 11-hydroxy-THC, a more potent compound that produces a longer-lasting, more psychedelic high.
2. Top 10 Reasons You’re Not Getting High From Marijuana
Why aren’t you experiencing a high after consuming cannabis? Several factors can contribute to this. Here are ten of the most prevalent reasons you might not be feeling the desired effects.
2.1 First Time Using Cannabis
Many first-time cannabis users report either a different kind of high or no high at all. Several factors influence this. Beginners may not inhale correctly, especially without guidance from experienced users. Some theories suggest that the lack of a high is due to underlying physiological factors. Over time, the body increases the number of cannabinoid receptors to accommodate THC, a process called receptor upregulation. Beginners have fewer receptors, meaning THC has fewer binding sites to produce its effects.
2.2 Not Knowing What to Expect
Your expectations can significantly impact your experience. If you don’t know what to anticipate, you might miss subtle effects. Many first-timers take only a few puffs and expect intense effects. However, this small amount may produce barely noticeable results, especially if the cannabis has a low THC content. Instead of dismissing this as a failed attempt, pay attention to minor shifts in mood, thoughts, and physical sensations. This approach allows you to gradually introduce yourself to cannabis.
2.3 Not Inhaling Properly
Incorrect inhalation is a common reason why first-time smokers don’t get high. If you’ve never smoked before, you might experience a harsh sensation in your throat and cough. Many beginners simply inhale into their mouth and immediately exhale. This may produce a slight high, but it won’t unlock cannabis’s full potential. Instead, draw the smoke deeply into your lungs. You don’t need to hold it in, but make sure you inhale deeply before exhaling. This ensures that THC molecules enter your bloodstream, maximizing the effects.
2.4 Using a Poor-Quality Product
Beginners often fall into two categories: those with experienced friends who guide them and those who navigate the terrain alone. The former typically have access to high-quality cannabis from the start, while the latter may end up using poor-quality products. High-quality buds are well-manicured, properly dried, and coated with trichomes. Poor-quality buds are often seedy, wet, untrimmed, and low in THC. Even with proper inhalation, you may experience a mediocre high at best.
2.5 Not Using Enough Weed
Uncertainty is common among beginners, leading them to use too little cannabis. The composition of what you’re smoking also matters. Smokers in the United States and Canada often use only cannabis flowers when rolling a joint, increasing the likelihood of getting high. In contrast, many European smokers add tobacco, making the joint seem bulkier. This can give the impression that you are smoking more cannabis than you actually are. Additionally, the nicotine rush from tobacco can be mistaken for a THC high. While it’s good to start slowly, don’t hesitate to use more cannabis if you don’t feel the desired effects after the first few attempts.
2.6 The Weed Contains More CBD Than THC
Cannabis breeders have developed strains with high levels of cannabidiol, or CBD, in recent years. CBD does not produce intoxicating effects but can leave users feeling relaxed and alert. Some strains have equal amounts of THC and CBD, while others contain high levels of CBD and almost no THC. If you are not feeling high, check the cannabinoid profile of the strain to ensure it contains enough THC to achieve the desired effect.
2.7 Wrong Consumption Method
Starting with complex consumption methods can make getting high more difficult. While fancy vaporizers, water pipes, and electronic dab rigs may seem appealing, their complicated operation can lead to errors and hinder the experience. Smoking a simple joint is recommended for first-time cannabis use. This allows you to experience all the cannabinoids and terpenes that cannabis offers. From there, you can explore bongs, bubblers, and pipes. Once you are comfortable with these methods, you can move on to edibles, dabbing, and vaping without issues.
2.8 High Tolerance
It’s not just beginners who struggle to get high. Experienced smokers can also miss the full effects of THC. After prolonged use, the number of CB1 receptors in the body increases initially but then decreases with chronic exposure to THC. This leads to desensitization to the psychotropic cannabinoid over time, requiring more cannabis to achieve the same effects. This phenomenon is known as tolerance. Taking a short break from cannabis can restore CB1 receptor expression to normal, typically taking from two days to two weeks.
2.9 Endocannabinoid Deficiency
Although debated among cannabis industry professionals, clinical endocannabinoid deficiency (CECD) describes a physiological state where the body produces low levels of endocannabinoids. These molecules act as chemical messengers, aiding various bodily systems, from digestion to the nervous system. Each person has a unique “endocannabinoid tone,” or the amount of endocannabinoids their body produces. Cannabinoids like THC share traits with endocannabinoids, allowing them to bind to the same receptors. If someone has an endocannabinoid deficiency, THC may only restore their endocannabinoid tone to a baseline level, meaning they may need more cannabis to feel psychotropic effects. This is just conjecture, though.
2.10 Are Hormones Blocking Your Cannabis High?
Hormones can also influence how cannabis affects you. Hormone levels vary among individuals. Pregnenolone, produced by the adrenal glands, is a building block for steroid hormones like oestrogen and DHEA. High levels of these hormones may reduce the cannabis high by blocking THC’s effect on CB1 receptors. Therefore, a person with high pregnenolone levels may need higher doses of THC to feel comparable effects. Pregnenolone levels can be tested through a doctor’s appointment.
3. What to Do If You Don’t Get High on Cannabis
If you don’t get high the first few times you smoke weed, don’t be discouraged. It’s a common experience. Try a few more times to allow your body to adjust. You might have a breakthrough on your third or fourth attempt. Sometimes, your unique physiology is the reason. Reduced endocannabinoid tone or higher hormone levels may mean you require more THC. Alternatively, smoking may not be the best method for you; vaping, eating, or drinking cannabis may be more effective. Eventually, you’ll find the perfect dose and method that works best for you.
4. Exploring the Science Behind Cannabis and the “High”
To better understand why some individuals might not experience a high from cannabis, it’s essential to delve deeper into the science behind how cannabis interacts with the body. The primary active compound in cannabis, THC, binds to cannabinoid receptors in the brain and body, particularly the CB1 receptors, which are predominantly found in the central nervous system. This interaction triggers a cascade of neurochemical events that lead to the psychoactive effects commonly associated with being “high.” However, several factors can influence this process, potentially diminishing or nullifying the high.
4.1 The Endocannabinoid System (ECS)
The ECS is a complex network of receptors, endogenous cannabinoids (produced by the body), and enzymes that regulate various physiological processes, including mood, pain sensation, appetite, and immune response. The ECS plays a crucial role in maintaining homeostasis, or balance, within the body. When THC enters the system, it mimics the effects of endocannabinoids, disrupting this balance and leading to the characteristic effects of cannabis use.
4.2 Receptor Sensitivity and Density
The sensitivity and density of cannabinoid receptors can vary significantly from person to person. Individuals with a higher density of CB1 receptors or more sensitive receptors may experience more pronounced effects from THC. Conversely, those with fewer or less sensitive receptors may require a higher dose to achieve the same level of intoxication.
4.3 Enzyme Activity
Enzymes are responsible for breaking down endocannabinoids and THC in the body. The activity of these enzymes can influence the duration and intensity of cannabis effects. Individuals with higher enzyme activity may metabolize THC more quickly, leading to a shorter or less intense high.
4.4 The Role of Genetics
Genetic factors can also play a significant role in how an individual responds to cannabis. Certain genetic variations can affect the expression and function of cannabinoid receptors, as well as the metabolism of THC. These genetic differences can help explain why some people are more sensitive to the effects of cannabis than others.
5. Psychological and Environmental Factors
Beyond the biological and chemical aspects, psychological and environmental factors can also impact the cannabis experience. These factors can influence how an individual perceives and responds to the effects of THC.
5.1 Set and Setting
“Set” refers to an individual’s mindset, expectations, and emotional state at the time of consumption. “Setting” refers to the physical and social environment in which cannabis is consumed. A positive mindset and a comfortable, safe environment can enhance the cannabis experience, while a negative mindset or an uncomfortable setting can diminish or even counteract the desired effects.
5.2 Prior Experiences and Expectations
Past experiences with cannabis can shape an individual’s expectations and influence their subsequent experiences. If someone has had negative experiences with cannabis in the past, they may be more likely to anticipate negative effects and, as a result, have a less enjoyable experience. Conversely, positive experiences can create positive expectations, leading to a more pleasant and fulfilling high.
5.3 Social Context
The social context in which cannabis is consumed can also affect the experience. Consuming cannabis with friends or in a social setting can enhance feelings of relaxation, sociability, and enjoyment. On the other hand, consuming cannabis alone or in an environment where one feels judged or uncomfortable can lead to anxiety, paranoia, and a diminished high.
6. Addressing Common Misconceptions
There are several common misconceptions about cannabis and its effects that can contribute to confusion and frustration when individuals don’t experience the expected high. Addressing these misconceptions can help individuals approach cannabis use with more realistic expectations and a better understanding of their own unique responses.
6.1 “All Cannabis is the Same”
One of the most pervasive misconceptions is that all cannabis is the same. In reality, there is a wide variety of cannabis strains, each with its own unique chemical profile and effects. Different strains can contain varying levels of THC, CBD, and other cannabinoids, as well as different terpenes, which contribute to their aroma and effects. Choosing the right strain is crucial for achieving the desired experience.
6.2 “More THC Always Means a Better High”
Another common misconception is that a higher THC content automatically translates to a better or more intense high. While THC is the primary psychoactive compound in cannabis, it is not the only factor that determines the overall experience. Other cannabinoids, terpenes, and individual factors can all play a role. In some cases, strains with lower THC content but a diverse range of other compounds may provide a more balanced and enjoyable experience.
6.3 “Edibles are Always Stronger”
Edibles can be significantly more potent than smoked or vaporized cannabis, but this is not always the case. The effects of edibles can vary depending on the dose, the individual’s metabolism, and whether they have eaten recently. It is important to start with a low dose of edibles and wait at least two hours before taking more to avoid overconsumption.
7. Practical Tips for Enhancing Your Cannabis Experience
If you’re consistently not getting high from cannabis, there are several practical steps you can take to enhance your experience and increase the likelihood of achieving the desired effects.
7.1 Experiment with Different Strains and Products
As mentioned earlier, different cannabis strains and products can have varying effects. Experimenting with different options can help you find what works best for you. Consider trying strains with different ratios of THC to CBD, as well as different terpene profiles. You may also want to explore different consumption methods, such as smoking, vaping, edibles, or tinctures.
7.2 Adjust Your Dosage
Dosage is a crucial factor in determining the effects of cannabis. If you’re not getting high enough, try increasing your dose gradually. However, it’s important to proceed with caution, especially when using edibles. Start with a small increase and wait at least two hours before taking more.
7.3 Improve Your Inhalation Technique
If you’re smoking or vaping cannabis, make sure you’re inhaling properly. Take slow, deep breaths and hold the smoke or vapor in your lungs for a few seconds before exhaling. This allows more THC to be absorbed into your bloodstream.
7.4 Take a Tolerance Break
If you’re a frequent cannabis user, you may have developed a tolerance to THC. Taking a tolerance break, even for just a few days, can help reset your system and make you more sensitive to the effects of cannabis.
7.5 Optimize Your Set and Setting
Create a positive and comfortable environment for your cannabis use. Choose a setting where you feel safe, relaxed, and free from distractions. Surround yourself with friends or loved ones who share your interest in cannabis and can contribute to a positive social experience.
7.6 Stay Hydrated and Nourished
Dehydration and hunger can both diminish the cannabis experience. Make sure you’re drinking plenty of water and eating nutritious meals before and after consuming cannabis. This will help your body metabolize THC more efficiently and enhance the overall effects.
8. Seeking Professional Guidance
If you’ve tried various strategies and are still not getting the desired effects from cannabis, it may be helpful to seek professional guidance. Consulting with a healthcare provider or a cannabis expert can provide valuable insights and personalized recommendations.
8.1 Consult with a Healthcare Provider
A healthcare provider can assess your overall health and identify any underlying medical conditions that may be affecting your response to cannabis. They can also provide guidance on safe and responsible cannabis use, as well as potential interactions with medications you may be taking.
8.2 Seek Advice from a Cannabis Expert
Cannabis experts, such as budtenders at licensed dispensaries, can offer valuable insights into different cannabis strains and products, as well as consumption methods and dosage recommendations. They can also provide information on local laws and regulations related to cannabis use.
9. Staying Informed and Up-to-Date
The world of cannabis is constantly evolving, with new research emerging regularly. Staying informed and up-to-date on the latest developments can help you make more informed decisions about your cannabis use and optimize your experience.
9.1 Follow Reputable Sources of Information
There are numerous sources of information about cannabis, but not all are created equal. Stick to reputable sources, such as scientific journals, government agencies, and established cannabis news outlets. Be wary of unverified claims or sensationalized reporting.
9.2 Participate in Cannabis Communities
Engaging with other cannabis enthusiasts can provide valuable insights and support. Join online forums, attend local cannabis events, or connect with like-minded individuals on social media. Sharing experiences and knowledge can help you learn more about cannabis and find new ways to enhance your experience.
10. Embracing the Journey
Ultimately, the cannabis experience is a personal and unique one. There is no one-size-fits-all approach, and it may take some experimentation and self-discovery to find what works best for you. Embrace the journey, stay curious, and be patient with yourself. With the right knowledge and approach, you can unlock the full potential of cannabis and enjoy a safe, fulfilling, and enjoyable experience.
FAQ: Common Questions About Cannabis and Its Effects
Q1: Why do some people not get high the first time they use cannabis?
A1: First-time users may not inhale properly or have fewer cannabinoid receptors, reducing THC’s ability to bind and produce effects.
Q2: Can the type of cannabis strain affect whether I get high?
A2: Yes. Strains with higher THC levels are more likely to produce a high, while those with more CBD may have milder or non-intoxicating effects.
Q3: How does tolerance affect the cannabis high?
A3: Over time, regular cannabis use can lead to tolerance, reducing the intensity of the high and requiring more cannabis to achieve the same effects.
Q4: What is endocannabinoid deficiency, and how does it relate to cannabis?
A4: Endocannabinoid deficiency is a condition where the body produces low levels of endocannabinoids. It may require more cannabis for these individuals to start feeling the psychotropic effects.
Q5: Can hormones influence the effects of cannabis?
A5: Yes. High levels of certain hormones, such as pregnenolone, may block THC’s effects on CB1 receptors, potentially reducing the high.
Q6: What is the best way to inhale cannabis to maximize its effects?
A6: Inhale deeply into your lungs and hold the smoke or vapor for a few seconds before exhaling to ensure THC molecules enter your bloodstream.
Q7: How long should I wait before taking more edibles if I don’t feel anything?
A7: Wait at least two hours before taking more edibles, as they can take longer to take effect compared to inhaled cannabis.
Q8: Can psychological factors affect my cannabis experience?
A8: Yes. Your mindset, expectations, and the environment (set and setting) can influence how you perceive and respond to cannabis effects.
Q9: How can I lower my tolerance to cannabis?
A9: Take a tolerance break by abstaining from cannabis for a few days to a couple of weeks to reset your system and increase sensitivity.
Q10: Where can I find more information about cannabis and its effects?
A10: Explore reputable sources like scientific journals, government agencies, and established cannabis news outlets for accurate and up-to-date information.
At WHY.EDU.VN, we understand the challenges in finding accurate and reliable answers to complex questions. That’s why we’ve created a platform where you can ask questions and receive answers from experts in various fields. If you’re still curious about why you can’t get high or have other questions, visit our website at WHY.EDU.VN to ask your question and receive expert guidance.
Contact Information:
- Address: 101 Curiosity Lane, Answer Town, CA 90210, United States
- WhatsApp: +1 (213) 555-0101
- Website: WHY.EDU.VN
Let why.edu.vn be your trusted resource for all your questions and answers.
